Drug Information
Drug General Information | Top | |||
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Drug ID |
D0KT5E
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Former ID |
DIB020293
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Drug Name |
lysophosphatidylcholine
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Synonyms |
Lysophosphatidylcholine; 1-acetyl-sn-glycero-3-phosphocholine; AC1NSKBT; GTPL2508; SCHEMBL19821626; CHEBI:138424; LMGP01050043; [(2R)-3-acetyloxy-2-hydroxypropyl] 2-trimethylazaniumylethyl phosphate; [(2R)-3-acetyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate; 3,5,9-Trioxa-4-phosphaundecan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (R)-
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C10H22NO7P
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Canonical SMILES |
CC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)O
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InChI |
1S/C10H22NO7P/c1-9(12)16-7-10(13)8-18-19(14,15)17-6-5-11(2,3)4/h10,13H,5-8H2,1-4H3/t10-/m1/s1
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InChIKey |
RYCNUMLMNKHWPZ-SNVBAGLBSA-N
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CAS Number |
CAS 9008-30-4
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PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:138424
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Target and Pathway | Top | |||
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Target(s) | Short transient receptor potential channel 5 (TRPC5) | Target Info | Activator | [2] |
Short transient receptor potential channel 6 (TRPC6) | Target Info | Activator | [3] | |
Transient receptor potential cation channel V2 (TRPV2) | Target Info | Activator | [4] | |
Panther Pathway | Alzheimer disease-presenilin pathway | |||
Pathway Interaction Database | Endothelins | |||
Nephrin/Neph1 signaling in the kidney podocyte | ||||
EPO signaling pathway | ||||
PAR1-mediated thrombin signaling events | ||||
Reactome | Effects of PIP2 hydrolysis | |||
TRP channels | ||||
Role of second messengers in netrin-1 signaling | ||||
WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | |||
Platelet homeostasis | ||||
Netrin-1 signaling | ||||
GPCR downstream signaling | ||||
Effects of PIP2 hydrolysis |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2508). | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 490). | |||
REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 491). | |||
REF 4 | Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation. Biochim Biophys Acta. 2009 Mar;1793(3):528-39. |
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