Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KB2E
|
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| Former ID |
DNC000662
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| Drug Name |
FR167356
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| Indication | Osteoporosis [ICD-11: FB83.0; ICD-10: M85.8; ICD-9: 733.9] | Preclinical | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C19H17Cl2NO3
|
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| Canonical SMILES |
CC1=C(C2=C(O1)C(=CC=C2)NC(=O)C3=C(C=CC=C3Cl)Cl)C(C)(C)O
|
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| InChI |
1S/C19H17Cl2NO3/c1-10-16(19(2,3)24)11-6-4-9-14(17(11)25-10)22-18(23)15-12(20)7-5-8-13(15)21/h4-9,24H,1-3H3,(H,22,23)
|
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| InChIKey |
GCAOVMKRBUCSET-UHFFFAOYSA-N
|
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| CAS Number |
CAS 174185-16-1
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vacuolar-type proton ATPase (v-ATPase) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Lysosomes as a therapeutic target. Nat Rev Drug Discov. 2019 Dec;18(12):923-948. | |||
| REF 2 | Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res. 2012 Jan;40(Database issue):D1128-36. | |||
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