Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0K7CX
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| Former ID |
DIB020016
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| Drug Name |
HT1042
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| Synonyms |
5-(3-nitrophenyl)-1,3,4-oxathiazol-2-one; CHEMBL3265177; 23589-77-7; NSC294566; AC1L6WL8; GTPL8649; SCHEMBL1781484; DTXSID10315430; BDBM50010993
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C8H4N2O4S
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| Canonical SMILES |
C1=CC(=CC(=C1)[N+](=O)[O-])C2=NSC(=O)O2
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| InChI |
1S/C8H4N2O4S/c11-8-14-7(9-15-8)5-2-1-3-6(4-5)10(12)13/h1-4H
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| InChIKey |
QBAZATRGWRVUFN-UHFFFAOYSA-N
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| CAS Number |
CAS 23589-77-7
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| PubChem Compound ID | ||||
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Proteasome beta-8 (PS beta-8) | Target Info | Inhibitor | [2] |
| References | Top | |||
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| REF 1 | Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol. 2011 Dec 25;13(2):129-35. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2408). | |||
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