Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0K1VK
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| Former ID |
DCL000481
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| Drug Name |
AZD8055
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| Synonyms |
AZD8055; 1009298-09-2; AZD-8055; AZD 8055; [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol; (5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol; UNII-970JJ37FPW; 970JJ37FPW; CHEMBL1801204; AK109550; (5-(2,4-Bis((S)-3-methylmorpholino)pyrido-[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol; (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Discontinued in Phase 1/2 | [1], [2] | |
| Company |
AstraZeneca
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| Structure |
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Download2D MOL |
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| Formula |
C25H31N5O4
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| Canonical SMILES |
CC1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOCC5C
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| InChI |
1S/C25H31N5O4/c1-16-14-33-10-8-29(16)24-20-5-6-21(18-4-7-22(32-3)19(12-18)13-31)26-23(20)27-25(28-24)30-9-11-34-15-17(30)2/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17-/m0/s1
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| InChIKey |
KVLFRAWTRWDEDF-IRXDYDNUSA-N
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| CAS Number |
CAS 1009298-09-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
58097209, 85072236, 104253209, 124757335, 125164139, 126661324, 134448064, 135267308, 135727412, 135727825, 136350023, 136355138, 136367461, 136920284, 137085457, 141539260, 143499728, 144115670, 152234788, 152258210, 152344230, 160647046, 161004367, 162011428, 162037664, 162202602, 162767680, 163408556, 163848038, 163907981, 164043014, 164834153, 172912365, 174525766, 177748865, 185998818, 187072938, 198965343, 204428794, 223366047, 223373666, 223621254, 223652808, 223704778, 223716957, 224340601, 226639481, 246319398, 249854406, 251971026
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| ChEBI ID |
CHEBI:91329
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7714). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028731) | |||
| REF 3 | Clinical pipeline report, company report or official report of AstraZeneca (2009). | |||
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