Drug Information
Drug General Information | Top | |||
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Drug ID |
D0K0QU
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Former ID |
DNC009192
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Drug Name |
(+)-(5S,8S,10S)-20-methoxypuupehenol
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Synonyms |
CHEMBL459185; (+)-(5S,8S,10S)-20-methoxypuupehenol; BDBM50242017; (+)-(5S,8S,9R,10S)-15,20-Dimethoxypuupehenol
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C23H34O4
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Canonical SMILES |
CC1(CCCC2(C1CCC3(C2C(C4=CC(=C(C=C4O3)O)OC)OC)C)C)C
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InChI |
1S/C23H34O4/c1-21(2)9-7-10-22(3)18(21)8-11-23(4)20(22)19(26-6)14-12-17(25-5)15(24)13-16(14)27-23/h12-13,18-20,24H,7-11H2,1-6H3/t18-,19+,20+,22-,23-/m0/s1
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InChIKey |
JAGJWSBNJZPDNL-FCSJJDFTSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 12-lipoxygenase (12-LOX) | Target Info | Inhibitor | [1] |
Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] | |
BioCyc | Resolvin D biosynthesis | |||
Lipoxin biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Linoleic acid metabolism | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
Pathway Interaction Database | IL4-mediated signaling events | |||
WikiPathways | Arachidonic acid metabolism | |||
Eicosanoid Synthesis |
References | Top | |||
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REF 1 | Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. J Nat Prod. 2003 Feb;66(2):230-5. |
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