Drug Information
Drug General Information | Top | |||
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Drug ID |
D0JM7Z
|
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Drug Name |
ASP8062
|
|||
Indication | Fibromyalgia [ICD-11: MG30.01; ICD-10: M79.7; ICD-9: 729.1] | Phase 2 | [1] | |
Company |
Astellas Northbrook, IL
|
Target and Pathway | Top | |||
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Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Modulator | [1] |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
GABAergic synapse | ||||
Estrogen signaling pathway | ||||
Morphine addiction | ||||
Reactome | Activation of G protein gated Potassium channels | |||
G alpha (i) signalling events | ||||
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Potassium Channels | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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