Drug Information
Drug General Information | Top | |||
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Drug ID |
D0JF6W
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Drug Name |
PMID28870136-Compound-65
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Drug Type |
Small molecular drug
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Company |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC
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Structure |
Download2D MOL |
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Formula |
C23H23N5O
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Canonical SMILES |
CN1CCC(CC1)N2C(=O)C=CC(=N2)C3=C4C=CC=CN4N=C3C5=CC=CC=C5
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InChI |
1S/C23H23N5O/c1-26-15-12-18(13-16-26)28-21(29)11-10-19(24-28)22-20-9-5-6-14-27(20)25-23(22)17-7-3-2-4-8-17/h2-11,14,18H,12-13,15-16H2,1H3
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InChIKey |
YHDRUTMZCJZJAL-UHFFFAOYSA-N
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CAS Number |
CAS 202646-80-8
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Ecto-5'-nucleotidase (CD73) | Target Info | Inhibitor | [1] |
Target's Patent Info | Ecto-5'-nucleotidase (CD73) | Target's Patent Info | [1] | |
BioCyc | Purine nucleotides degradation | |||
Urate biosynthesis/inosine 5'-phosphate degradation | ||||
Adenosine nucleotides degradation | ||||
KEGG Pathway | Purine metabolism | |||
Pyrimidine metabolism | ||||
Nicotinate and nicotinamide metabolism | ||||
Metabolic pathways | ||||
Panther Pathway | Purine metabolism | |||
Pyrimidine Metabolism | ||||
Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
Reactome | Purine catabolism | |||
WikiPathways | Differentiation Pathway | |||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Metabolism of nucleotides |
References | Top | |||
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REF 1 | Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304. |
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