Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0JF0W
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| Former ID |
DIB020698
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| Drug Name |
PGF1alpha
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| Synonyms |
U 18714; prostaglandin F1alpha
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H36O5
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| Canonical SMILES |
CCCCCC(C=CC1C(CC(C1CCCCCCC(=O)O)O)O)O
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| InChI |
1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18-,19+/m0/s1
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| InChIKey |
DZUXGQBLFALXCR-CDIPTNKSSA-N
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| CAS Number |
CAS 745-62-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
8707, 855641, 4266053, 8616452, 14717675, 14803240, 24898704, 26751470, 26751471, 39289907, 47364930, 48184753, 49959067, 50103977, 57357939, 80706395, 92309908, 99300822, 99302340, 104046438, 113854257, 124799810, 126524626, 134223489, 135061652, 137131166, 160687826, 162228441, 178102065, 179205562, 184548058, 198958986, 227684304, 241130843, 250133980, 252356261, 252455632, 252457345, 252469076
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| ChEBI ID |
CHEBI:28852
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cation channel sperm-associated protein (CatSper) | Target Info | Activator | [2] |
| Cation channel sperm-associated protein 1 (CatSper1) | Target Info | Activator | [2] | |
| Cation channel sperm-associated protein 2 (CatSper2) | Target Info | Activator | [2] | |
| Cation channel sperm-associated protein 3 (CatSper3) | Target Info | Activator | [2] | |
| WikiPathways | Fertilization | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5412). | |||
| REF 2 | Progesterone activates the principal Ca2+ channel of human sperm. Nature. 2011 Mar 17;471(7338):387-91. | |||
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