Drug Information
Drug General Information | Top | |||
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Drug ID |
D0J7MQ
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Former ID |
DIB000865
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Drug Name |
MKC-1106-MT
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Synonyms |
Melanoma vaccine (MART-1/tyrosinase), Mannkind
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Indication | Melanoma [ICD-11: 2C30; ICD-9: 172] | Phase 2 | [1] | |
Company |
Colby pharmaceuticals
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Target and Pathway | Top | |||
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Target(s) | MART-1 melanoma antigen (MLANA) | Target Info | Modulator | [2] |
Tyrosinase (TYR) | Target Info | Modulator | [2] | |
BioCyc | (S)-reticuline biosynthesis | |||
Eumelanin biosynthesis | ||||
L-dopachrome biosynthesis | ||||
KEGG Pathway | Tyrosine metabolism | |||
Riboflavin metabolism | ||||
Metabolic pathways | ||||
Melanogenesis | ||||
Pathwhiz Pathway | Riboflavin Metabolism | |||
Tyrosine Metabolism | ||||
WikiPathways | Dopamine metabolism |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01026051) Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma. U.S. National Institutes of Health. | |||
REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. |
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