Drug Information
Drug General Information | Top | |||
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Drug ID |
D0J3VV
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Former ID |
DIB000732
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Drug Name |
IPH-3201
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Synonyms |
IPH-32XX; TLR-7 modulators (cancer), Cancer Research Technology; TLR-7 modulators (cancer), Innate; Toll-like receptor 7 modulators (cancer), Innate
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Terminated | [1] | |
Company |
Cancer Research Technology Ltd
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Target and Pathway | Top | |||
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Target(s) | Toll-like receptor 7 (TLR7) | Target Info | Modulator | [2] |
KEGG Pathway | Toll-like receptor signaling pathway | |||
Measles | ||||
Influenza A | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | Toll receptor signaling pathway | |||
Reactome | Trafficking and processing of endosomal TLR | |||
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | ||||
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | ||||
MyD88 dependent cascade initiated on endosome | ||||
WikiPathways | Toll-like receptor signaling pathway | |||
Toll-Like Receptors Cascades | ||||
MyD88 dependent cascade initiated on endosome | ||||
Trafficking and processing of endosomal TLR | ||||
Regulation of toll-like receptor signaling pathway |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026574) | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1757). |
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