Drug Information
Drug General Information | Top | |||
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Drug ID |
D0J3TS
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Former ID |
DNC014633
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Drug Name |
6-Thiophen-2-yl-imidazo[2,1-b]thiazole
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Synonyms |
6-(thiophen-2-yl)imidazo[2,1-b][1,3]thiazole; AC1Q7FWK; AC1N51XV; CHEMBL12113; IFLab2_000013; IFLab1_003798; MolPort-000-476-548; HMS1422M14; ZINC406855; STL115074; CCG-22586; AKOS002232733; MCULE-2716534216; 6-(2-Thienyl)imidazo[2,1-b]thiazole; IDI1_019039; IDI1_009905; imidazo[2,1-b]thiazole,6-(2-thienyl)-; KB-305118; EU-0080970; ST50113084; 6-(2-thienyl)imidazo[2,1-b]1,3-thiazoline; 6-thiophen-2-ylimidazo[2,1-b][1,3]thiazole; SR-01000506671
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C9H6N2S2
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Canonical SMILES |
C1=CSC(=C1)C2=CN3C=CSC3=N2
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InChI |
1S/C9H6N2S2/c1-2-8(12-4-1)7-6-11-3-5-13-9(11)10-7/h1-6H
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InChIKey |
YKINBJCTANWRJC-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | NADH dehydrogenase (MT-ND3) | Target Info | Inhibitor | [1] |
KEGG Pathway | Oxidative phosphorylation | |||
Metabolic pathways | ||||
Parkinson's disease | ||||
WikiPathways | Oxidative phosphorylation | |||
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
Electron Transport Chain |
References | Top | |||
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REF 1 | Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase. J Med Chem. 1995 Mar 31;38(7):1090-7. |
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