Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J1OG
|
|||
| Drug Name |
Prolanta
|
|||
| Indication | Fallopian tube cancer [ICD-11: 2C74; ICD-10: C57.0] | Phase 1 | [1] | |
| Ovarian cancer [ICD-11: 2C73; ICD-10: C56; ICD-9: 183] | Phase 1 | [1] | ||
| Peritoneal cavity cancer [ICD-11: 2C51.Z] | Phase 1 | [1] | ||
| Company |
Oncolix Houston, TX
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prolactin receptor (PRLR) | Target Info | Antagonist | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Neuroactive ligand-receptor interaction | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Prolactin signaling pathway | ||||
| Pathway Interaction Database | ErbB4 signaling events | |||
| Signaling events mediated by PTP1B | ||||
| Reactome | Prolactin receptor signaling | |||
| Growth hormone receptor signaling | ||||
| WikiPathways | Ovarian Infertility Genes | |||
| Prolactin receptor signaling | ||||
| Growth hormone receptor signaling | ||||
| Adipogenesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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