Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0IZ4Z
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| Former ID |
DNC008889
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| Drug Name |
3-[4-(4-Hydroxyphenyl)-1,3-oxazol-2-yl]phenol
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| Synonyms |
CHEMBL529446; 3-[4-(4-Hydroxyphenyl)-1,3-oxazol-2-yl]phenol; SCHEMBL1180107; BDBM50271078
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H11NO3
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| Canonical SMILES |
C1=CC(=CC(=C1)O)C2=NC(=CO2)C3=CC=C(C=C3)O
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| InChI |
1S/C15H11NO3/c17-12-6-4-10(5-7-12)14-9-19-15(16-14)11-2-1-3-13(18)8-11/h1-9,17-18H
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| InChIKey |
NOWYSMIMXQPTPC-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Estradiol 17 beta-dehydrogenase 1 (17-beta-HSD1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Estradiol biosynthesis I | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Reactome | The canonical retinoid cycle in rods (twilight vision) | |||
| WikiPathways | Steroid Biosynthesis | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Prostate Cancer | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid ... Bioorg Med Chem. 2008 Jun 15;16(12):6423-35. | |||
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