Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0IQ6R
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| Drug Name |
US8598172, 1
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| Synonyms |
SCHEMBL1527199; CHEMBL3660143; BDBM108214; US8598172, 1
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H34F3N7O2
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| Canonical SMILES |
CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=CC(=C4)N5CCN(CC5)C)OC(F)(F)F)C
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| InChI |
1S/C26H34F3N7O2/c1-4-20-24(37)34(3)21-16-30-25(32-23(21)36(20)17-7-5-6-8-17)31-19-15-18(35-13-11-33(2)12-14-35)9-10-22(19)38-26(27,28)29/h9-10,15-17,20H,4-8,11-14H2,1-3H3,(H,30,31,32)/t20-/m1/s1
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| InChIKey |
UKDYPCZCLRCOMP-HXUWFJFHSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Polo-like kinase 2 (PLK2) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Polo-like kinase 2 (PLK2) | Target's Patent Info | [1] | |
| KEGG Pathway | FoxO signaling pathway | |||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TSH Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| TCR Signaling Pathway | ||||
| Pathway Interaction Database | PLK2 and PLK4 events | |||
| Polo-like kinase signaling events in the cell cycle | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors. US8598172. | |||
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