Drug Information
Drug General Information | Top | |||
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Drug ID |
D0I8MP
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Former ID |
DNC013347
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Drug Name |
N-(1-(3-bromobenzyl)piperidin-4-yl)-2-naphthamide
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Synonyms |
CHEMBL395867; N-(1-(3-bromobenzyl)piperidin-4-yl)-2-naphthamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C23H23BrN2O
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Canonical SMILES |
C1CN(CCC1NC(=O)C2=CC3=CC=CC=C3C=C2)CC4=CC(=CC=C4)Br
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InChI |
1S/C23H23BrN2O/c24-21-7-3-4-17(14-21)16-26-12-10-22(11-13-26)25-23(27)20-9-8-18-5-1-2-6-19(18)15-20/h1-9,14-15,22H,10-13,16H2,(H,25,27)
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InChIKey |
KMQWTBGTEFASGU-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part II: Influence of the substitution on the benzyl moiety on the a... Bioorg Med Chem Lett. 2007 Mar 15;17(6):1570-4. |
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