Drug Information
Drug General Information | Top | |||
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Drug ID |
D0I7FF
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Former ID |
DNC008164
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Drug Name |
1,1,1-trifluorododecan-2-one
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Synonyms |
1,1,1-trifluorododecan-2-one; CHEMBL86668; 26902-72-7; 2-Dodecanone, 1,1,1-trifluoro-; AC1L424F; 1,1,1-Trifluoro-2-dodecanone; BDBM50371959
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H21F3O
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Canonical SMILES |
CCCCCCCCCCC(=O)C(F)(F)F
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InChI |
1S/C12H21F3O/c1-2-3-4-5-6-7-8-9-10-11(16)12(13,14)15/h2-10H2,1H3
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InChIKey |
YXTBWTOMSMZIMA-UHFFFAOYSA-N
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CAS Number |
CAS 26902-72-7
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Fatty acid amide hydrolase (FAAH) | Target Info | Inhibitor | [1] |
Liver carboxylesterase (CES1) | Target Info | Inhibitor | [1] | |
BioCyc | Anandamide degradation | |||
KEGG Pathway | Retrograde endocannabinoid signaling | |||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Panther Pathway | Anandamide degradation | |||
Pathway Interaction Database | E2F transcription factor network | |||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Heroin metabolism | ||||
Irinotecan Pathway | ||||
Fluoropyrimidine Activity | ||||
Phase I biotransformations, non P450 |
References | Top | |||
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REF 1 | Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hy... Bioorg Med Chem. 2008 Feb 15;16(4):2114-30. |
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