Drug Information
Drug General Information | Top | |||
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Drug ID |
D0I5GS
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Drug Name |
CAR.CD30 cells
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Drug Type |
CAR T Cell Therapy
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Indication | Immune System disease [ICD-11: 4A01-4B41] | Phase 1/2 | [1], [2] | |
Immunoproliferative disorder [ICD-11: 2B32; ICD-10: D47.9] | Phase 1/2 | [1], [2] | ||
Lymphatic disease [ICD-11: BD9Z] | Phase 1/2 | [1], [2] | ||
Lymphoma [ICD-11: 2A80-2A86; ICD-9: 202.8, 208.9] | Phase 1/2 | [1], [2] | ||
Neoplasm [ICD-11: 2A00-2F9Z] | Phase 1/2 | [1], [2] | ||
Company |
UNC Lineberger Comprehensive Cancer Center
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Target and Pathway | Top | |||
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Target(s) | Lymphocyte activation antigen CD30 (TNFRSF8) | Target Info | CAR-T-Cell-Therapy | [1], [2] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
NetPath Pathway | Leptin Signaling Pathway | |||
TCR Signaling Pathway |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT02663297) Administration of T Lymphocytes for Prevention of Relapse of Lymphomas | |||
REF 2 | ClinicalTrials.gov (NCT02690545) Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL |
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