Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I3EI
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| Former ID |
DIB010893
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| Drug Name |
NK-1001
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| Synonyms |
NNYK-1001; NYK-1001
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| Drug Type |
Small molecular drug
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| Indication | Atrial fibrillation [ICD-11: BC81.3; ICD-10: I48] | Discontinued in Phase 2 | [1] | |
| Company |
Nyken BV
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| Structure |
 |
Download2D MOL |
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| Formula |
C18H35N3O12
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| Canonical SMILES |
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)O)O)OC3C(C(C(C(O3)CN)O)O)O)N
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| InChI |
1S/C18H35N3O12/c19-2-6-8(23)10(25)12(27)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)11(26)9(24)7(3-22)31-18/h4-18,22-29H,1-3,19-21H2/t4-,5+,6-,7-,8-,9-,10+,11+,12-,13-,14-,15+,16-,17-,18-/m1/s1
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| InChIKey |
NZCOZAMBHLSNDW-GUKOCFKPSA-N
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| CAS Number |
CAS 53025-93-7
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Heat shock protein 27 (HSP27) | Target Info | Modulator | [2] |
| Heat shock protein 70 (HSP70) | Target Info | Modulator | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033456) | |||
| REF 2 | Novel therapeutic targets in the management of atrial fibrillation. Am J Cardiovasc Drugs. 2014 Dec;14(6):403-21. | |||
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