Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I1RP
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| Former ID |
DNC005026
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| Drug Name |
2-(4-Fluoro-indole-1-sulfonyl)-benzoic acid
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| Synonyms |
CHEMBL362888; 2-(4-Fluoro-indole-1-sulfonyl)-benzoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H10FNO4S
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| Canonical SMILES |
C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N2C=CC3=C2C=CC=C3F
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| InChI |
1S/C15H10FNO4S/c16-12-5-3-6-13-10(12)8-9-17(13)22(20,21)14-7-2-1-4-11(14)15(18)19/h1-9H,(H,18,19)
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| InChIKey |
YQOPLEXTOUMMNP-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid-binding protein 4 (FABP4) | Target Info | Inhibitor | [1] |
| KEGG Pathway | PPAR signaling pathway | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathway Interaction Database | AP-1 transcription factor network | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| Transcriptional regulation of white adipocyte differentiation | ||||
| WikiPathways | Lipid digestion, mobilization, and transport | |||
| Transcriptional Regulation of White Adipocyte Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8. | |||
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