Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I0SY
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| Former ID |
DIB001164
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| Drug Name |
MEDI-542
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| Synonyms |
Ephrin a4-targeting monoclonal antibody (cancer), MedImmune
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| Drug Type |
Antibody
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Terminated | [1] | |
| Company |
Medlmmune LLC
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ephrin type-A receptor 4 (EPHA4) | Target Info | . | [2] |
| KEGG Pathway | Axon guidance | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | EphrinA-EPHA pathway | |||
| EPHA forward signaling | ||||
| Reactome | EPH-Ephrin signaling | |||
| EPHA-mediated growth cone collapse | ||||
| EPH-ephrin mediated repulsion of cells | ||||
| WikiPathways | Gene regulatory network modelling somitogenesis | |||
| Spinal Cord Injury | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021498) | |||
| REF 2 | Product Pipeline Review of MedImmune, LLC in 2012. | |||
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