Drug Information
Drug General Information | Top | |||
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Drug ID |
D0H6ZC
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Drug Name |
RWJ-387273
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Synonyms |
R-290629; oral PDE 5 inhibitor (erectile dysfunction), Johnson & Johnson
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C24H19N3O2
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Canonical SMILES |
C1COC2=C1C=C(C=C2)C3C4=C(CN3C5=CC=CC=N5)C(=O)C6=CC=CC=C6N4
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InChI |
1S/C24H19N3O2/c28-24-17-5-1-2-6-19(17)26-22-18(24)14-27(21-7-3-4-11-25-21)23(22)16-8-9-20-15(13-16)10-12-29-20/h1-9,11,13,23H,10,12,14H2,(H,26,28)/t23-/m1/s1
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InChIKey |
NPQHDOLBQQVPMG-HSZRJFAPSA-N
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CAS Number |
CAS 374927-41-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Phosphodiesterase 5A (PDE5A) | Target Info | Modulator | [1] |
KEGG Pathway | Purine metabolism | |||
cGMP-PKG signaling pathway | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
Reactome | cGMP effects |
References | Top | |||
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REF 1 | DOI: 10.1021/op060099f |
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