Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0H4GN
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| Former ID |
DAP000693
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| Drug Name |
Desflurane
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| Synonyms |
Desflurano; Desfluranum; Suprane; I 653; I653; PC6781E; Desflurane [USAN:INN]; Desflurano [INN-Spanish]; Desfluranum [INN-Latin]; I-653; R-e 236ea1; Suprane (TN); Desflurane (JAN/USP/INN); Difluoromethyl 1,2,2,2-tetrafluoroethyl ether; (+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether; 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane; 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1], [2] | |
| Therapeutic Class |
Anesthetics
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| Structure |
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Download2D MOL |
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| Formula |
C3H2F6O
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| Canonical SMILES |
C(C(F)(F)F)(OC(F)F)F
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| InChI |
1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H
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| InChIKey |
DPYMFVXJLLWWEU-UHFFFAOYSA-N
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| CAS Number |
CAS 57041-67-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9722, 3160485, 4908648, 7847612, 7979042, 8177466, 11533490, 12014271, 15219463, 34707669, 46505270, 49966554, 57312650, 76342437, 95695185, 103770716, 104338752, 117502900, 125372049, 127770141, 131499044, 132511024, 134222145, 134337982, 135004119, 135590730, 137008121, 139078453, 143456975, 160964523, 162874517, 163693523, 164808504, 172873428, 178103731, 179150679, 184555027, 206257182, 224228880, 226444351, 249913775, 251888228, 252365870, 252492104
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| ChEBI ID |
CHEBI:4445
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| ADReCS Drug ID | BADD_D00611 | |||
| SuperDrug ATC ID |
N01AB07
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| SuperDrug CAS ID |
cas=057041675
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Antagonist | [3] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7156). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020118. | |||
| REF 3 | Modulation of NMDA receptor function by ketamine and magnesium. Part II: interactions with volatile anesthetics. Anesth Analg. 2001 May;92(5):1182-91. | |||
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