Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H2UM
|
|||
| Former ID |
DNC005027
|
|||
| Drug Name |
2-(5-Bromo-indole-1-sulfonyl)-benzoic acid
|
|||
| Synonyms |
CHEMBL184005; 2-(5-Bromo-indole-1-sulfonyl)-benzoic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C15H10BrNO4S
|
|||
| Canonical SMILES |
C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N2C=CC3=C2C=CC(=C3)Br
|
|||
| InChI |
1S/C15H10BrNO4S/c16-11-5-6-13-10(9-11)7-8-17(13)22(20,21)14-4-2-1-3-12(14)15(18)19/h1-9H,(H,18,19)
|
|||
| InChIKey |
RGZDWZUMVMDEAG-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid-binding protein 4 (FABP4) | Target Info | Inhibitor | [1] |
| KEGG Pathway | PPAR signaling pathway | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathway Interaction Database | AP-1 transcription factor network | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| Transcriptional regulation of white adipocyte differentiation | ||||
| WikiPathways | Lipid digestion, mobilization, and transport | |||
| Transcriptional Regulation of White Adipocyte Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.