Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H0WK
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| Former ID |
DNAP001706
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| Drug Name |
Gadofosveset
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| Synonyms |
Vasovist (TN)
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| Drug Type |
Small molecular drug
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| Indication | Imaging [ICD-11: QA0B; ICD-10: W88] | Approved | [1] | |
| Company |
Epix
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| Structure |
 |
Download2D MOL
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| Formula |
C33H41GdN3O14P
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| Canonical SMILES |
[H+].[H+].[H+].C1CC(CCC1OP(=O)([O-])OCC(CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-])(C2=CC=CC=C2)C3=CC=CC=C3.[Gd+3]
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| InChI |
1S/C33H44N3O14P.Gd/c37-28(38)18-34(15-16-35(19-29(39)40)20-30(41)42)17-26(36(21-31(43)44)22-32(45)46)23-49-51(47,48)50-27-11-13-33(14-12-27,24-7-3-1-4-8-24)25-9-5-2-6-10-25;/h1-10,26-27H,11-23H2,(H,37,38)(H,39,40)(H,41,42)(H,43,44)(H,45,46)(H,47,48);/q;+3/p-3/t26-;/m1./s1
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| InChIKey |
ZSDLYSDDELEVDD-UFTMZEDQSA-K
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| CAS Number |
CAS 201688-00-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ADReCS Drug ID | BADD_D00987 ; BADD_D00988 | |||
| SuperDrug ATC ID |
V08CA11
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serum albumin (ALB) | Target Info | Modulator | [1] |
| Pathway Interaction Database | FOXA2 and FOXA3 transcription factor networks | |||
| Reactome | Platelet degranulation | |||
| Recycling of bile acids and salts | ||||
| HDL-mediated lipid transport | ||||
| Scavenging of heme from plasma | ||||
| WikiPathways | Human Complement System | |||
| Binding and Uptake of Ligands by Scavenger Receptors | ||||
| Lipid digestion, mobilization, and transport | ||||
| Transport of vitamins, nucleosides, and related molecules | ||||
| Bile acid and bile salt metabolism | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2008 FDA drug approvals. Nat Rev Drug Discov. 2009 Feb;8(2):93-6. | |||
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