Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0GR1Y
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| Drug Name |
Minnelide
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| Synonyms |
UNII-1CIV2UMO40; 1CIV2UMO40; 14-O-Phosphonooxymethyltriptolide disodium salt; CHEMBL3740500; Triptolide O-Methyl Phosphate Disodium Salt; Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-C)furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt (1:2), (3bS,4aS,5aR,6R,6aS,7aS,7bS,8aS,8bS)-; 1254702-87-8
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z] | Phase 1 | [1] | |
| Company |
Minneamrita Therapeutics Tampa, FL
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| Structure |
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Download2D MOL |
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| Formula |
C21H25Na2O10P
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| Canonical SMILES |
CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2OCOP(=O)([O-])[O-])O7)COC6=O)C.[Na+].[Na+]
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| InChI |
1S/C21H27O10P.2Na/c1-9(2)19-14(30-19)15-21(31-15)18(3)5-4-10-11(7-26-16(10)22)12(18)6-13-20(21,29-13)17(19)27-8-28-32(23,24)25;;/h9,12-15,17H,4-8H2,1-3H3,(H2,23,24,25);;/q;2*+1/p-2/t12-,13-,14-,15-,17+,18-,19-,20+,21+;;/m0../s1
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| InChIKey |
ZHBJMVNZRZUQEP-KIKMAQITSA-L
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| CAS Number |
CAS 1254702-87-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Heat shock protein 70 (HSP70) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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