Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GE4A
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| Former ID |
DNC013215
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| Drug Name |
N-butyl-2-(1H-indol-3-yl)-2-oxoacetamide
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| Synonyms |
CHEMBL223476; N-butyl-2-(1H-indol-3-yl)-2-oxoacetamide; N-Butyl-2-(1H-indol-3-yl)-2-oxo-acetamide; BAS 04280181; AC1MK4QP; MolPort-000-249-106; ZINC3635496; BDBM50206948; N-butyl-2-indol-3-yl-2-oxoacetamide; AKOS000530602; MCULE-8866008030; ST50101897
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H16N2O2
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| Canonical SMILES |
CCCCNC(=O)C(=O)C1=CNC2=CC=CC=C21
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| InChI |
1S/C14H16N2O2/c1-2-3-8-15-14(18)13(17)11-9-16-12-7-5-4-6-10(11)12/h4-7,9,16H,2-3,8H2,1H3,(H,15,18)
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| InChIKey |
XTLXOIBNXHXNBR-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Serotonergic synapse | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-... J Med Chem. 2007 Apr 5;50(7):1627-34. | |||
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