Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GC2M
|
|||
| Former ID |
DAP000857
|
|||
| Drug Name |
Acamprosate
|
|||
| Synonyms |
AOTA; Acamprosato; Acamprosatum; Acamprostate; Aotal; Campral; Calcium acetyl homotaurinate; Calcium acetylhomotaurinate; Calcium acetylhomotaurine; Sodium acetylhomotaurine; Acamprosate 6473; Acamprosate (Campral); Acamprosate (INN); Acamprosate [INN:BAN]; Acamprosato [INN-Spanish]; Acamprosatum [INN-Latin]; Aotal (TN); Campral (TN); N-Acetylhomotaurine; 3-(Acetylamino)propanesulphonic acid; 3-Acetamido-1-propanesulfonic acid; 3-acetamidopropane-1-sulfonic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Alcohol dependence [ICD-11: 6C40.2; ICD-10: F10.2; ICD-9: 303] | Approved | [1], [2] | |
| Therapeutic Class |
Alcohol Deterrents
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C5H11NO4S
|
|||
| Canonical SMILES |
CC(=O)NCCCS(=O)(=O)O
|
|||
| InChI |
1S/C5H11NO4S/c1-5(7)6-3-2-4-11(8,9)10/h2-4H2,1H3,(H,6,7)(H,8,9,10)
|
|||
| InChIKey |
AFCGFAGUEYAMAO-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 77337-76-9
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
8194463, 15120629, 43127539, 46506657, 50021914, 51091400, 56464352, 57318038, 75557048, 103810289, 104349795, 117362127, 117633800, 124955684, 125691474, 127397498, 131327164, 132554646, 134224179, 134338136, 135027346, 137002470, 141750083, 160964004, 162912604, 175267284, 178103683, 179151136, 223536069, 226426881, 241137131, 243433170, 250136754
|
|||
| ChEBI ID |
CHEBI:51041
|
|||
| ADReCS Drug ID | BADD_D00016 ; BADD_D00017 | |||
| SuperDrug ATC ID |
N07BB03
|
|||
| SuperDrug CAS ID |
cas=077337769
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Agonist | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7106). | |||
| REF 2 | The effects of acamprosate on alcohol-cue reactivity and alcohol priming in dependent patients: a randomized controlled trial. Psychopharmacology (Berl). 2009 Jul;205(1):53-62. | |||
| REF 3 | Predicting the effect of naltrexone and acamprosate in alcohol-dependent patients using genetic indicators. Addict Biol. 2009 Jul;14(3):328-37. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.