Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0GB8J
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| Former ID |
DNC012971
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| Drug Name |
(S)-2-amino-2-cyclohexylacetic acid
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| Synonyms |
14328-51-9; h-chg-oh; l-alpha-cyclohexylglycine; L-Cyclohexylglycine; (S)-2-amino-2-cyclohexylacetic acid; h-cyclohexyl-gly-oh; L-(+)-2-Cyclohexylglycine; (2s)-amino(cyclohexyl)acetic acid; CYCLOHEXYLGLYCYL; 2-Cyclohexyl-L-glycine; (2S)-2-amino-2-cyclohexylacetic acid; CYCLOHEXYL-GLYCINE; l-cyclohexyl glycine; (s)-cyclohexylglycine; L-2-Cyclohexylglycine; h-cyclohexyl-d-gly-oh; CHEMBL382372; UNII-59Q5O5615E; (S)-Amino-cyclohexyl-acetic acid; (2S)-amino(cyclohexyl)ethanoic acid; MFCD01311679; 59Q5O5615E; l-(-)-cyclohexylglycine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H15NO2
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| Canonical SMILES |
C1CCC(CC1)C(C(=O)O)N
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| InChI |
1S/C8H15NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h6-7H,1-5,9H2,(H,10,11)/t7-/m0/s1
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| InChIKey |
WAMWSIDTKSNDCU-ZETCQYMHSA-N
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| CAS Number |
CAS 14328-51-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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