Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GA8I
|
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| Drug Name |
ATLCAR.CD30 cells
|
|||
| Drug Type |
CAR T Cell Therapy
|
|||
| Indication | Immune System disease [ICD-11: 4A01-4B41] | Phase 1 | [1] | |
| Immunoproliferative disorder [ICD-11: 2B32; ICD-10: D47.9] | Phase 1 | [1] | ||
| Lymphatic disease [ICD-11: BD9Z] | Phase 1 | [1] | ||
| Lymphoma [ICD-11: 2A80-2A86; ICD-9: 202.8, 208.9] | Phase 1 | [1] | ||
| Neoplasm [ICD-11: 2A00-2F9Z] | Phase 1 | [1] | ||
| Company |
UNC Lineberger Comprehensive Cancer Center
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Lymphocyte activation antigen CD30 (TNFRSF8) | Target Info | CAR-T-Cell-Therapy | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| NetPath Pathway | Leptin Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03602157) Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and NHL | |||
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