Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0G8TM
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| Former ID |
DIB018061
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| Drug Name |
(+)-5-(5-bromothiophen-3-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid
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| Synonyms |
CHEMBL375493; GTPL1589; SCHEMBL3111157; BDBM50208137; (+)-5-(5-bromothiophen-3-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid; 5-(5-bromothiophen-3-yl)-5-methyl-4-oxofuran-2-carboxylic acid; 5-(5-bromothiophen-3-yl)-5-methyl-4-oxo-4,5-dihydrofuran-2-carboxylic acid; (+)-5-(5-bromo-thiophen-3-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid; 5-(5-bromo-thiophen-3-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C10H7BrO4S
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| Canonical SMILES |
CC1(C(=O)C=C(O1)C(=O)O)C2=CSC(=C2)Br
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| InChI |
1S/C10H7BrO4S/c1-10(5-2-8(11)16-4-5)7(12)3-6(15-10)9(13)14/h2-4H,1H3,(H,13,14)
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| InChIKey |
WJDLYZAOTHNUJX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nicotinic acid receptor (HCAR2) | Target Info | Agonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1589). | |||
| REF 2 | (D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. J Biol Chem. 2005 Jul 22;280(29):26649-52. | |||
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