Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G7NE
|
|||
| Former ID |
DNC009251
|
|||
| Drug Name |
2,7-diaminoanthraquinone
|
|||
| Synonyms |
2,7-Diaminoanthraquinone; 2,7-Diaminoanthrachinon; BRN 2809381; 605-44-7; 2,7-Diaminoanthrachinon [Czech]; 2,7-diaminoanthracene-9,10-dione; 9,10-Anthracenedione, 2,7-diamino- (9CI); ANTHRAQUINONE, 2,7-DIAMINO-; 9,10-Anthracenedione, 2,7-diamino-; AC1L1Y5O; SCHEMBL3135129; CHEMBL454957; CTK5B1667; DTXSID20209235; KJNHYKBXQOSFJR-UHFFFAOYSA-N; ZINC31483469; 9,10-Anthracenedione,2,7-diamino-; AKOS030561506
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H10N2O2
|
|||
| Canonical SMILES |
C1=CC2=C(C=C1N)C(=O)C3=C(C2=O)C=CC(=C3)N
|
|||
| InChI |
1S/C14H10N2O2/c15-7-1-3-9-11(5-7)14(18)12-6-8(16)2-4-10(12)13(9)17/h1-6H,15-16H2
|
|||
| InChIKey |
KJNHYKBXQOSFJR-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 605-44-7
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
| KEGG Pathway | HTLV-I infection | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
| Regulation of Telomerase | ||||
| IL2 signaling events mediated by PI3K | ||||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
| WikiPathways | TGF beta Signaling Pathway | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Telomere Maintenance | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.