Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0G6SD
|
|||
Former ID |
DAP000183
|
|||
Drug Name |
Delavirdine
|
|||
Synonyms |
DLV; Rescriptor; SPP; DELAVIRDINE MESYLATE; Delavirdine [INN]; U 90152; BHAP-U 90152; Delavirdine (INN); Rescriptor (TM);Rescriptor (TN); U-90152; U-90152S; PNU-90152-T; Delavirdine (*Mesylate salt*); U90152S (*Mesylate salt*); Delavirdine(U-90152) & .a.IFN; N-[2-[4-[3-(propan-2-ylamino)pyridin-2-yl]piperazine-1-carbonyl]-1H-indol-5-yl]methanesulfonamide; N-(2-(1-(3-(isopropylamino)pyridin-2-yl)piperazine-4-carbonyl)-1H-indol-5-yl)methanesulfonamide; N-[2-({4-[3-(propan-2-ylamino)pyridin-2-yl]piperazin-1-yl}carbonyl)-1H-indol-5-yl]methanesulfonamide; N-{2-[(4-{3-[(1-methylethyl)amino]pyridin-2-yl}piperazin-1-yl)carbonyl]-1H-indol-5-yl}methanesulfonamide; N-{2-[4-(3-Isopropylamino-pyridin-2-yl)-piperazine-1-carbonyl]-1H-indol-5-yl}-methanesulfonamide; Piperazine, 1-[3-[(1-methylethyl)amino]-2-pyridinyl]-4-[[5-[(methylsulfonyl)amino]-1H-indol-2-yl]carbonyl]-& alpha-Interferon; (1-(5-METHANSULPHONAMIDO-1H-INDOL-2-YL-CARBONYL)4-[METHYLAMINO)PYRIDINYL]PIPERAZINE; (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide); 1-(3-((1-Methylethyl)amino)-2-pyridinyl)-4-((5-((methylsulfonyl)amino)-1H-indol-2-yl)carbonyl)piperazine; 1-(5-Methanesulphonamido)-1H-indol-2-yl-carbonyl)-4-[3-(isopropylamino)-2-pyridinyl]piperaz; 2-(4-(5-Methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamine
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Approved | [1] | |
Therapeutic Class |
Anti-HIV Agents
|
|||
Company |
Pfizer Pharmaceuticals
|
|||
Structure |
Download2D MOL |
|||
Formula |
C22H28N6O3S
|
|||
Canonical SMILES |
CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C
|
|||
InChI |
1S/C22H28N6O3S/c1-15(2)24-19-5-4-8-23-21(19)27-9-11-28(12-10-27)22(29)20-14-16-13-17(26-32(3,30)31)6-7-18(16)25-20/h4-8,13-15,24-26H,9-12H2,1-3H3
|
|||
InChIKey |
WHBIGIKBNXZKFE-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 136817-59-9
|
|||
PubChem Compound ID | ||||
PubChem Substance ID |
9156, 600721, 633105, 4700507, 7890564, 7979035, 8031779, 8153462, 14857955, 29224663, 46508878, 48415852, 50064377, 50113278, 50860318, 53788602, 57322873, 57580870, 87350530, 92308796, 96024480, 99445034, 103181784, 104309776, 124893554, 125822848, 126653075, 126666446, 129580604, 134337503, 134358669, 135022528, 137006542, 142315847, 144206190, 152104495, 160964049, 163122160, 163693522, 164788294, 170464664, 172913431, 172919202, 175267271, 176484193, 179149870, 184546189, 196107220, 198992860, 204376689
|
|||
ChEBI ID |
CHEBI:119573
|
|||
ADReCS Drug ID | BADD_D00603 ; BADD_D00604 | |||
SuperDrug ATC ID |
J05AG02
|
|||
SuperDrug CAS ID |
cas=136817599
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Modulator | [2] |
References | Top | |||
---|---|---|---|---|
REF 1 | Approved antiretroviral drugs. Antiretroviral Drugs. Company report of AVERT. 2009. | |||
REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.