Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0G4PZ
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| Former ID |
DNC011284
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| Drug Name |
N-phenethyl-2-phenylquinoline-4-carboxamide
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| Synonyms |
N-phenethyl-2-phenylquinoline-4-carboxamide; 2-Phenyl-quinoline-4-carboxylic acid phenethyl-amide; 65628-69-5; BAS 00329480; ChemDiv3_013317; AC1MIR97; Oprea1_331981; Oprea1_089083; CBDivE_013546; CHEMBL1278237; CTK1I2246; DTXSID50389216; MolPort-001-924-745; HMS1510N07; ZINC3036412; AKOS000577213; MCULE-8602191420; NCGC00320157-01; EU-0063663; AB01317027-02; SR-01000583017; SR-01000583017-1; BRD-K88997350-001-01-1; 4-Quinolinecarboxamide, 2-phenyl-N-(2-phenylethyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C24H20N2O
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| Canonical SMILES |
C1=CC=C(C=C1)CCNC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
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| InChI |
1S/C24H20N2O/c27-24(25-16-15-18-9-3-1-4-10-18)21-17-23(19-11-5-2-6-12-19)26-22-14-8-7-13-20(21)22/h1-14,17H,15-16H2,(H,25,27)
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| InChIKey |
LVSGZPVWALHPET-UHFFFAOYSA-N
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| CAS Number |
CAS 65628-69-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuromedin-K receptor (TACR3) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Virtual screening to identify novel antagonists for the G protein-coupled NK3 receptor. J Med Chem. 2010 Nov 25;53(22):8080-8. | |||
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