Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FJ1N
|
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| Drug Name |
PMID30107136-Compound-Example42
|
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| Drug Type |
Small molecule immunotherapy
|
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| Indication | Hepatitis [ICD-11: DB97.Z] | Patented | [1] | |
| Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Patented | [1] | ||
| Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] | Patented | [1] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
| Company |
INCYTE CORPORATION
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C26H29N5O2
|
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| Canonical SMILES |
CN1C=C(C=N1)CCNC2CCN(CC2)C3=CC=CC(=C3C#N)C4=CC5=C(C=C4)OCCO5
|
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| InChI |
1S/C26H29N5O2/c1-30-18-19(17-29-30)7-10-28-21-8-11-31(12-9-21)24-4-2-3-22(23(24)16-27)20-5-6-25-26(15-20)33-14-13-32-25/h2-6,15,17-18,21,28H,7-14H2,1H3
|
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| InChIKey |
YIQQKUGTBUPKTJ-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target Info | Inhibitor | [1] |
| Target's Patent Info | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678. | |||
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