Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FI8L
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| Former ID |
DNC000980
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| Drug Name |
N1-guanyl-1,7-diaminoheptane
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H22N4+2
|
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| Canonical SMILES |
C(CCC[NH3+])CCC[NH+]=C(N)N
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| InChI |
1S/C8H20N4/c9-6-4-2-1-3-5-7-12-8(10)11/h1-7,9H2,(H4,10,11,12)/p+2
|
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| InChIKey |
YAOAMZOGXBMLFQ-UHFFFAOYSA-P
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Deoxyhypusine synthase (DHPS) | Target Info | Inhibitor | [1] |
| BioCyc | Hypusine biosynthesis | |||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| WikiPathways | PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture. Biochim Biophys Acta. 1996 Jan 10;1310(1):119-26. | |||
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