Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FF3D
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| Former ID |
DNC000929
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| Drug Name |
Metazamide
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| Synonyms |
METAZAMIDE; UNII-T3Y0F5VOB8; 14058-90-3; GPA-878; T3Y0F5VOB8; Metazamidum; 1-(4-methoxyphenyl)-5-methyl-2,3-dihydro-1H-imidazol-2-one; Metazamide [INN]; Metazamid; GPA 878; AC1L1B4L; 3-(4-methoxyphenyl)-4-methyl-1H-imidazol-2-one; 1-(4-Methoxyphenyl)-5-methyl-4-imidazolin-2-on; ZINC472; SCHEMBL193544; CHEMBL2104723; DTXSID80161441; MolPort-027-352-367; AKOS017548002; 1-(p-Methoxyphenyl)-5-methyl-4-imidazolin-2-one; 4-Imidazolin-2-one, 1-(4-methoxyphenyl)-5-methyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C11H12N2O2
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| Canonical SMILES |
CC1=CNC(=O)N1C2=CC=C(C=C2)OC
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| InChI |
1S/C11H12N2O2/c1-8-7-12-11(14)13(8)9-3-5-10(15-2)6-4-9/h3-7H,1-2H3,(H,12,14)
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| InChIKey |
NHUPEUMBGMETKD-UHFFFAOYSA-N
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| CAS Number |
CAS 14058-90-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glucose-6-phosphate dehydrogenase (G6PD) | Target Info | Inhibitor | [1] |
| BioCyc | Pentose phosphate pathway | |||
| Pentose phosphate pathway (oxidative branch) | ||||
| KEGG Pathway | Pentose phosphate pathway | |||
| Glutathione metabolism | ||||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Carbon metabolism | ||||
| Central carbon metabolism in cancer | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathwhiz Pathway | Pentose Phosphate Pathway | |||
| Warburg Effect | ||||
| Reactome | TP53 Regulates Metabolic Genes | |||
| WikiPathways | Sulfation Biotransformation Reaction | |||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Vitamin D Receptor Pathway | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Cori Cycle | ||||
| Metabolism of carbohydrates | ||||
| Pentose Phosphate Pathway | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Glucose utilization and activity of glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and malate dehydrogenase in rat erythrocytes after treatment with tuberculostatic agents. Vopr Med Khim. 1986 Sep-Oct;32(5):32-5. | |||
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