Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F9FR
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| Former ID |
DNC001071
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| Drug Name |
Oxazolidinones
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| Synonyms |
2-Oxazolidone; Oxazolidin-2-one; 2-Oxazolidinone; 497-25-6; 1,3-Oxazolidin-2-one; Oxazolidinone; Oxazolidone; UNII-Z4D49W92PP; EINECS 207-840-9; NSC 35382; BRN 0106251; AI3-38980; CHEBI:1237; Z4D49W92PP; IZXIZTKNFFYFOF-UHFFFAOYSA-N; Carbamic acid, (2-hydroxyethyl)-, gamma-lactone; MFCD00005268; 2-Oxazolidone, 98%; WLN: T5MVOTJ; 51667-26-6; Carbamic acid, .gamma.-lactone; Oxazolidinones; SMR000857362; oxazolodinone; hydroxyoxazoline; 2-oxazolidinon; hydroxy-oxazoline; 2-Oxazolidine; oxazolidine-2-one; PubChem8624; ACMC-209upq; AC1Q6HSI
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| Drug Type |
Small molecular drug
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| Indication | Gram-positive bacterial infection [ICD-11: 1B74-1G40] | Phase 2 | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C3H5NO2
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| Canonical SMILES |
C1COC(=O)N1
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| InChI |
1S/C3H5NO2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
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| InChIKey |
IZXIZTKNFFYFOF-UHFFFAOYSA-N
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| CAS Number |
CAS 497-25-6
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:1237
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial 16S ribosomal RNA (Bact 16S rRNA) | Target Info | Inhibitor | [2] |
| Bacterial 23S ribosomal RNA (Bact 23S rRNA) | Target Info | Inhibitor | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00646958) Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections. U.S. National Institutes of Health. | |||
| REF 2 | Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. RNA. 1999 Jul;5(7):939-46. | |||
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