Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0F8QJ
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| Former ID |
DNC014741
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| Drug Name |
WEDELOLACTONE
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| Synonyms |
Wedelolactone; 524-12-9; UNII-0K6L725GNS; 7-Methoxy-5,11,12-trihydroxycoumestan; 7-Methoxy-5,11,12-trihydroxy-coumestan; 1,8,9-Trihydroxy-3-methoxycoumestan; Wedelolactone, Eclipta alba; CHEMBL97453; 0K6L725GNS; CHEBI:10037; IKK Inhibitor II, Wedelolactone; 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one; 1,8,9-trihydroxy-3-methoxy-benzofuro[3,2-c]chromen-6-one; 1,8,9-Trihydroxy-3-methoxy-6H-[1]benzofuro[3,2-c]chromen-6-one; AC1NQZ4Z; SCHEMBL601220; GTPL5551; CTK8G3781; DTXSID60200408; Wedelolactone, analyti
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H10O7
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| Canonical SMILES |
COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O
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| InChI |
1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
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| InChIKey |
XQDCKJKKMFWXGB-UHFFFAOYSA-N
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| CAS Number |
CAS 524-12-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
12724, 6607120, 8616796, 10318945, 14850194, 24714965, 24724667, 26757046, 26758926, 29216425, 39315420, 47720877, 52815557, 57358404, 85293589, 103035852, 103311475, 103994110, 104225323, 113855998, 119501404, 121395213, 124892469, 126688973, 134351946, 135114815, 135685142, 135799242, 137019431, 139729856, 144087464, 144193938, 152036592, 162012094, 162224468, 163138675, 163687919, 164339342, 175607801, 178102193, 179236071, 198965475, 223672460, 226903835, 241090585, 249722325, 251915884, 251917232, 252406482
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| ChEBI ID |
CHEBI:10037
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5551). | |||
| REF 2 | Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation. Bioorg Med Chem Lett. 2001 Feb 12;11(3):283-6. | |||
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