Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F7ZH
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| Former ID |
DIB005263
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| Drug Name |
FXI-AS1
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| Synonyms |
FXI antisense oligonucleotides (thrombosis); FXI-AS2; FXI-ASO; ISIS-404071; FXI antisense oligonucleotides (thrombosis), Isis Pharmaceuticals; Factor XI antisense oligonucleotides (thrombosis), Isis Pharmaceuticals
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| Drug Type |
Antisense drug
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| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Investigative | [1] | |
| Company |
Isis Pharmaceuticals Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Factor XI messenger RNA (F11 mRNA) | Target Info | . | [1] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Pathwhiz Pathway | Coagulation | |||
| Reactome | Intrinsic Pathway of Fibrin Clot Formation | |||
| WikiPathways | Human Complement System | |||
| Blood Clotting Cascade | ||||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2360). | |||
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