Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F7WQ
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| Former ID |
DIB000488
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| Drug Name |
HE-2000
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| Synonyms |
Immunitin; Inactivin; Bromoepiandrosterone, Hollis-Eden; DHEA analogs, Hollis-Eden; Dehydroepiandrosterone, Hollis-Eden
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| Drug Type |
Small molecular drug
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| Indication | Cystic fibrosis [ICD-11: CA25; ICD-10: E84, E84.9; ICD-9: 277] | Discontinued in Phase 2 | [1] | |
| Company |
Colthurst Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C19H29BrO2
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| Canonical SMILES |
CC12CCC(CC1CCC3C2CCC4(C3CC(C4=O)Br)C)O
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| InChI |
1S/C19H29BrO2/c1-18-7-5-12(21)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(20)17(19)22/h11-16,21H,3-10H2,1-2H3/t11-,12-,13+,14-,15-,16+,18-,19-/m0/s1
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| InChIKey |
CWVMWSZEMZOUPC-JUAXIXHSSA-N
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| CAS Number |
CAS 28507-02-0
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010830) | |||
| REF 2 | Dehydroepiandrosterone upregulates neural androgen receptor level and transcriptional activity. J Neurobiol. 2003 Nov;57(2):163-71. | |||
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