Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0F1VR
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| Former ID |
DNC005189
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| Drug Name |
3,4-Dibromo-2-(5-bromo-2-hydroxy-phenoxy)-phenol
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| Synonyms |
CHEMBL187472; 3,4-Dibromo-2-(5-bromo-2-hydroxy-phenoxy)-phenol; Phenol, 3,4-dibromo-2-(5-bromo-2-hydroxyphenoxy)-; BDBM50150781; 741285-19-8; 5,5',6-Tribromo-2,2'-dihydroxydiphenyl ether
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H7Br3O3
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| Canonical SMILES |
C1=CC(=C(C=C1Br)OC2=C(C=CC(=C2Br)Br)O)O
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| InChI |
1S/C12H7Br3O3/c13-6-1-3-8(16)10(5-6)18-12-9(17)4-2-7(14)11(12)15/h1-5,16-17H
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| InChIKey |
MQTQEJZMDKSDNZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Resolvin D biosynthesis | |||
| Lipoxin biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Linoleic acid metabolism | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. J Med Chem. 2004 Jul 29;47(16):4060-5. | |||
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