Drug Information
Drug General Information | Top | |||
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Drug ID |
D0F1FN
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Former ID |
DNC004323
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Drug Name |
(2-Indol-1-yl-ethyl)-dimethyl-amine
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Synonyms |
1H-Indole-1-ethanamine, N,N-dimethyl-; CHEMBL38633; 87482-09-5; (2-Indol-1-yl-ethyl)-dimethyl-amine; SCHEMBL4060777; CTK3C3615; DTXSID80579188; PSHKCPACSIZILK-UHFFFAOYSA-N; (2-Indol-1-ylethyl)dimethylamine; BDBM50108308; N,N-Dimethyl-1H-indole-1-ethanamine; AKOS013123773; [2-(1H-indol-1-yl)ethyl]dimethylamine; 2-(1H-Indol-1-yl)-N,N-dimethylethan-1-amine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H16N2
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Canonical SMILES |
CN(C)CCN1C=CC2=CC=CC=C21
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InChI |
1S/C12H16N2/c1-13(2)9-10-14-8-7-11-5-3-4-6-12(11)14/h3-8H,9-10H2,1-2H3
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InChIKey |
PSHKCPACSIZILK-UHFFFAOYSA-N
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CAS Number |
CAS 87482-09-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors. Bioorg Med Chem Lett. 2002 Jan 21;12(2):155-8. |
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