Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F0OK
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| Former ID |
DAP001199
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| Drug Name |
Sulfametopyrazine
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| Synonyms |
Dalysep; Kelfizin; Kelfizina; Kelfizine; Longum; Polycidal; SMP; SULFALENE; Solfametopirazina; Sulfalen; Sulfaleno; Sulfalenum; Sulfamethopyrazine; Sulfamethoxypyrazine; Sulfamethoxysuccinate; Sulfametoxypyridazin; Sulfapyrazinemethoxine; Sulfapyrazinemethoxyine; Sulfapyrazinemethoxyne; Sulfapyrazinmethoxine; Sulphalene; Sulphametopyrazine; Kelfizine W; Solfametopirazina [DCIT]; AS 18908; CBMicro_013257; FI 5978; WR 4629; Farmitalia 204/122; Kelfizina (TN); Sulfalene (USAN); Sulfalene [USAN:INN]; Sulfaleno [INN-Spanish]; Sulfalenum [INN-Latin]; Sulfamethopyrazine (JAN); N1-(3-Methoxypyrazinyl)sulfanilamide; N(sup 1)-(3-Methoxypyrazinyl)sulfanilamide; N(sup1)-(3-Methoxypyrazinyl)sulfanilamide; N(sup 1)-(3-Methoxy-2-pyrazinyl)sulfanilamide; N(sup1)-(3-Methoxy-2-pyrazinyl)sulfanilamide; Sulfanilamide, N1-(3-methoxypyrazinyl)-(8CI); 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine; 2-(p-Aminobenzenesulfonamido)-3-methoxypyrazine; 2-Methoxy-3-sulfanilamidopyrazine; 2-Sulfanilamide 3-methoxy-pyrazine; 2-Sulfanilamido-3-methoxypyrazine; 3-Methoxy-2-sulfanilamidopyrazine; 3-Methoxy-2-sulfapyrazine; 3-Methoxypyrazine sulfanilamide; 4-Amino-N-(3-methoxy-pyrazin-2-yl)-benzenesulfonamide; 4-Amino-N-(3-methoxypyrazinyl)-benzenesulfonamide; 4-Amino-N-(3-methoxypyrazinyl)benzenesulfonamide; 4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
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| Drug Type |
Small molecular drug
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| Indication | Urinary tract infection [ICD-11: GC08; ICD-10: N39, N39.0; ICD-9: 599] | Withdrawn from market | [1] | |
| Therapeutic Class |
Antiinfective Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C11H12N4O3S
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| Canonical SMILES |
COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)N
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| InChI |
1S/C11H12N4O3S/c1-18-11-10(13-6-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
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| InChIKey |
KXRZBTAEDBELFD-UHFFFAOYSA-N
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| CAS Number |
CAS 152-47-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
409142, 583006, 604395, 7548079, 7848279, 8062608, 8156436, 11160573, 14799628, 17437592, 29216164, 29227665, 46505111, 47365723, 50048736, 50086577, 57325395, 58023655, 78686684, 81066133, 81093065, 92711298, 93373982, 104319411, 105085796, 124666553, 124766274, 124966247, 125170101, 125341730, 126603293, 126631009, 126657443, 126670666, 128449820, 131300043, 134338439, 134973755, 137003197, 143449411, 144052070, 144205397, 160964009, 162183044, 162211701, 163123923, 163412175, 163601400, 170031297, 170465930
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| ChEBI ID |
CHEBI:32162
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| SuperDrug ATC ID |
J01ED02
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| SuperDrug CAS ID |
cas=000152476
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Dihydropteroate synthetase (Bact folP) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Sulfametopyrazine, 2008. eduDrugs. | |||
| REF 2 | Plasmodium falciparum dihydrofolate reductase Val-16 and Thr-108 mutation associated with in vivo resistance to antifolate drug: a case study. Indian J Malariol. 2001 Sep-Dec;38(3-4):76-83. | |||
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