Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E8OO
|
|||
| Former ID |
DNC001883
|
|||
| Drug Name |
ISIS 4764
|
|||
| Drug Type |
Antisense drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Company |
Isis Pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | E-selectin messenger RNA (SELE mRNA) | Target Info | . | [1] |
| KEGG Pathway | Cell adhesion molecules (CAMs) | |||
| TNF signaling pathway | ||||
| African trypanosomiasis | ||||
| Malaria | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| IL4 Signaling Pathway | ||||
| TNFalpha Signaling Pathway | ||||
| ID Signaling Pathway | ||||
| Pathway Interaction Database | Thromboxane A2 receptor signaling | |||
| Glucocorticoid receptor regulatory network | ||||
| ATF-2 transcription factor network | ||||
| Reactome | Cell surface interactions at the vascular wall | |||
| WikiPathways | Human Complement System | |||
| TNF alpha Signaling Pathway | ||||
| Cell surface interactions at the vascular wall | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | US patent application no. 5,789,573, Antisense inhibition of ICAM-1, E-selectin, and CMV IE1/IE2. | |||
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