Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E8AS
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| Drug Name |
Tricyclic heterocycle derivative 6
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| Synonyms |
PMID25482888-Compound-55
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| Drug Type |
Small molecular drug
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| Company |
MERCK SHARP & DOHME CORP. BURNETT, Duane, A. ZHAO, Zhiqiang COLE, David JOSIEN, Hubert PISSARNITSKI, Dmitri, A. SASIKUMAR, Thavalakulamgar WU, Wen-Lian DOMALSKI, Martin
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| Structure |
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Download2D MOL |
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| Formula |
C22H29N7O4
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| Canonical SMILES |
CC#CCN1C2=C(N=C3N(C(=O)CN3C2=O)C)N=C1N4CCCC(C4)NC(=O)OC(C)(C)C
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| InChI |
1S/C22H29N7O4/c1-6-7-11-28-16-17(24-19-26(5)15(30)13-29(19)18(16)31)25-20(28)27-10-8-9-14(12-27)23-21(32)33-22(2,3)4/h14H,8-13H2,1-5H3,(H,23,32)/t14-/m1/s1
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| InChIKey |
CBLPHWVBNDVSJU-CQSZACIVSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dipeptidyl peptidase 4 (DPP-4) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Dipeptidyl peptidase 4 (DPP-4) | Target's Patent Info | [1] | |
| KEGG Pathway | Protein digestion and absorption | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DPP-4 inhibitors: a patent review (2012 - 2014).Expert Opin Ther Pat. 2015 Feb;25(2):209-36. | |||
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