Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E6NR
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| Former ID |
DIB006309
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| Drug Name |
BAY-Y-3118
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| Synonyms |
UNII-08VLU38WTI; BAY-Y-3118 free base; Bay-Y 3118; 08VLU38WTI; 151213-16-0; 144194-96-7; AC1L3OP2; SCHEMBL7502039; CHEMBL107544; DTXSID40164736; VRXORHRXNRJZCQ-ZUZCIYMTSA-N; BAY-Y-3118; HY-U00092; CS-7127; LS-194353; 8-Chloro-1-cyclopropyl-7-[(S,S)-2,8- diazobicyclo(4.3.0)-non-8-yl]-6-fluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acid, hydrochloride; 8-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[[(4aalpha,7aalpha)-octahydro-1H-pyrrolo[3,4-b]pyridin]-6-yl]quinoline-3-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Discontinued in Phase 2 | [1] | |
| Company |
Bayer AG
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| Structure |
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Download2D MOL |
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| Formula |
C20H21ClFN3O3
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| Canonical SMILES |
C1CC2CN(CC2NC1)C3=C(C=C4C(=C3Cl)N(C=C(C4=O)C(=O)O)C5CC5)F
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| InChI |
1S/C20H21ClFN3O3/c21-16-17-12(19(26)13(20(27)28)8-25(17)11-3-4-11)6-14(22)18(16)24-7-10-2-1-5-23-15(10)9-24/h6,8,10-11,15,23H,1-5,7,9H2,(H,27,28)/t10-,15+/m0/s1
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| InChIKey |
VRXORHRXNRJZCQ-ZUZCIYMTSA-N
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| CAS Number |
CAS 151213-51-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial DNA gyrase (Bact gyrase) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001782) | |||
| REF 2 | Bay Y 3118, a new quinolone derivative, rapidly eradicates Listeria monocytogenes from infected mice and L929 cells. | |||
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