Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E0HK
|
|||
| Former ID |
DNC003940
|
|||
| Drug Name |
2-Mercaptomethyl-pentanedioic acid
|
|||
| Synonyms |
2-Mercaptomethylglutaric acid; 2-Mercaptomethyl-pentanedioic acid; CHEMBL60941; 106146-19-4; Pentanedioic acid,2-(mercaptomethyl)-; 2-Mmga; 2-(sulfanylmethyl)pentanedioic acid; ACMC-1BUG7; AC1L2VT3; 2-mer-captomethylglutaric acid; SCHEMBL1278279; CTK4A4424; Glutaric acid, 2-mercaptomethyl-; LDFDXRPEWZHIML-UHFFFAOYSA-N; NSC613827; BDBM50127614
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C6H10O4S
|
|||
| Canonical SMILES |
C(CC(=O)O)C(CS)C(=O)O
|
|||
| InChI |
1S/C6H10O4S/c7-5(8)2-1-4(3-11)6(9)10/h4,11H,1-3H2,(H,7,8)(H,9,10)
|
|||
| InChIKey |
LDFDXRPEWZHIML-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 109333-27-9
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor. J Med Chem. 2003 May 8;46(10):1989-96. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.