Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0DW6V
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| Drug Name |
Pyrazole derivative 67
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| Synonyms |
PMID26609882-Compound-24
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| Drug Type |
Small molecular drug
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| Company |
ARENA PHARMACEUTICALS, INC. XIONG, Yifeng CHERRIER, Martin, C. CHOI, Jin Sun, Karoline DOSA, Peter, I. SMITH, Brian, M. STRAH-PLEYNET, Sonja ULLMAN, Bret TEEGARDEN, Bradley
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Antagonist | [1] |
| Target's Patent Info | 5-HT 2A receptor (HTR2A) | Target's Patent Info | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel serotonin receptor 2 (5-HT2R) agonists and antagonists: a patent review (2004-2014).Expert Opin Ther Pat. 2016;26(1):89-106. | |||
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