Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0DT1R
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| Former ID |
DNC001462
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| Drug Name |
Triapine
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| Synonyms |
Triapine; 236392-56-6; 143621-35-6; 3-Apct; Pan 811; 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP; UNII-U4XIL4091C; NSC 663249; 200933-27-3; OCX 191; 2-((3-Aminopyridin-2-yl)methylene)hydrazinecarbothioamide; C7H9N5S; PAN-811; U4XIL4091C; 3-aminopyridine-2-carbaldehyde-thiosemicarbazone; [(E)-(3-amino-2-pyridyl)methyleneamino]thiourea; 3-Aminopyridine-2-carboxaldehyde- thiosemicarbazone; Hydrazinecarbothioamide, 2-((3-amino-2-pyridinyl)methylene)-; (E)-2-((3-aminopyridin-2-yl)methylene)hydrazinecarbothioamide
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| Drug Type |
Small molecular drug
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| Indication | Nerve injury [ICD-11: ND56.4; ICD-10: T14.4] | Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H9N5S
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| Canonical SMILES |
C1=CC(=C(N=C1)C=NNC(=S)N)N
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| InChI |
1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+
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| InChIKey |
XMYKNCNAZKMVQN-NYYWCZLTSA-N
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| CAS Number |
CAS 143621-35-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
510133, 809489, 15322354, 23997063, 44710003, 49977503, 50630633, 53790121, 57372948, 103522243, 126680898, 132556347, 134340642, 135082505, 135156086, 137132427, 141862348, 162219716, 163417372, 164192051, 172836320, 172913921, 177218153, 184024310, 184024330, 184525729, 184525750, 184525771, 198986376, 210274660, 210280291, 223665245, 225380728, 226416462, 241035630, 249858431, 251971019, 252066194, 252499503, 252554240
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| References | Top | |||
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| REF 1 | PAN-811 inhibits oxidative stress-induced cell death of human Alzheimer's disease-derived and age-matched olfactory neuroepithelial cells via suppression of intracellular reactive oxygen species. J Alzheimers Dis. 2009;17(3):611-9. | |||
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