Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0D7FX
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| Former ID |
DNC012967
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| Drug Name |
Rac-2-amino-4-phenylbutanoic acid
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| Synonyms |
DL-Homophenylalanine; 1012-05-1; 2-Amino-4-phenylbutanoic acid; h-dl-hophe-oh; 2-Amino-4-phenylbutyric acid; (-)-2-Amino-4-phenylbutyric acid; H-DL-HOMOPHE-OH; H-DL-HPH-OH; 2-amino-4-phenyl-butyric acid; 7636-28-4; CHEMBL203873; Benzylalanine; JTTHKOPSMAVJFE-UHFFFAOYSA-N; Benzenebutanoic acid, alpha-amino-; (RS)-2-AMINO-4-PHENYL-BUTYRIC ACID; dlhpa; MFCD00063091; rac-2-amino-4-phenylbutanoic acid; d,l-homophenylalanine; ACMC-209tws; AC1L2SZU; DL-Homophenylalanine, 98%; KSC492S1B; SCHEMBL130567; AC1Q5S74; AC1Q50B0; KS-00000FXF
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H13NO2
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| Canonical SMILES |
C1=CC=C(C=C1)CCC(C(=O)O)N
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| InChI |
1S/C10H13NO2/c11-9(10(12)13)7-6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)
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| InChIKey |
JTTHKOPSMAVJFE-UHFFFAOYSA-N
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| CAS Number |
CAS 1012-05-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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